Childhood cancer mortality is disproportionately higher in low- and middle-income countries than high-income countries. The World Health Organization Global Initiative for Childhood Cancer aims for a survival of 60% by 2030. This initiative prioritizes timely diagnosis, access to standardized therapy and supportive care, and prompt management of treatment-related complications. Collaborative work is linked to better performance of health systems and delivery of high-quality care.

Objective

To evaluate the post-pandemic regulatory preparedness of countries of the Region of the Americas for emergency authorization of vaccines as of August 2024 and propose recommendations for future public health emergencies. 

Methods

Special report describing the mechanisms for emergency use authorization of vaccines established in the regulatory frameworks of Latin American and English-speaking Caribbean countries. 

Objective

Identify the factors associated with lack of maternal and child vaccination during the 2024–2025 pertussis outbreak in Mexico. 

Methods

Retrospective multicenter study in 20 hospitals across 10 states. Maternal Tdap vaccination (tetanus, diphtheria, and acellular pertussis vaccine) and compliance with the childhood vaccination schedule at 2, 4, 6, and 18 months were recorded. Both χ²/Fisher and Mann–Whitney tests were performed, in addition to logistical regressions to estimate aOR (CI 95%). 

Objective

Chronic noncommunicable diseases are the leading cause of death and disability worldwide, with devastating effects on household economies and national growth. The objective of this research is to investigate the knowledge and application of clinical practice guidelines in primary care in Argentina, and to identify barriers and facilitators in the use of evidence-based practices for diagnosis, access, and adherence to noncommunicable disease prevention and control. 

Objectives

Drug use disorders – preventable and treatable conditions – are a challenging and growing public health threat in the Region of the Americas. This study aims to provide a comprehensive analysis of the levels and trends of the burden of these disorders across countries in the Americas. 

Objective

Analyze the impact of the COVID-19 pandemic on influenza vaccination coverage in some countries in the Americas. 

Objective

To compare sociodemographic and clinical characteristics and the outcome severity between confirmed cases of Oropouche fever and dengue in the state of Espírito Santo, Brazil. 

Objective

Identify the social determinants of therapeutic adherence among users of the primary health care system’s cardiovascular health program (PSCV). 

Objective

To estimate the association of social determinants, the urban environment, and public policies with the occurrence and evolution over time of homicides in Santiago de Cali, Colombia (2015–2024), to inform decision-making in public health and territorial planning. 

Objective

Using Mexico as a case study, identify barriers and opportunities and formulate recommendations to strengthen management of type 1 diabetes mellitus (T1DM) in primary health care (PHC), with potential for implementation in other countries of the Region of the Americas.