PAHO/WHO evidence synthesis and recommendations

The Pan American Health Organization and the World Health Organization continuously develop evidence-informed guidelines that address major diseases affecting population health (guidelines available in the BIGG database). The guidelines are developed using a systematic and transparent approach called GRADE (Grading of Recommendations Assessment, Development and Evaluation).

Evidence synthesis and recommendations: clinical practice guidelines on drug treatment for hypertension in pregnancy

Introduction

Hypertensive disorders during pregnancy are a major cause of severe morbidity, long-term disability, and death. Appropriate pharmacological treatment is essential in the management of these disorders

Objetives

Synthesize the recommendations developed by the World Health Organization (WHO) to improve the quality of care and health outcomes of adults with high blood pressure, and address aspects of how to implement these recommendations.

The importance of basic and translational research in caring for children with malignant solid tumors in Latin America

Objective

Basic and translational research in pediatric cancer are essential to improve patient care. To critically assess the developments achieved in these areas in Latin America, we systematically reviewed information published between 2013 and 2023. 

Addressing childhood cancer: actions taken in the Dominican Republic

This report provides a summary of childhood cancer and the efforts made in the Dominican Republic to address child and adolescent cancer in line with the World Health Organization’s Global Initiative for Childhood Cancer. Information was obtained by review of recent local and international literature on pediatric oncology. As a result of the Global Initiative, a meeting was held by the Council of Ministers of Health of Central America to support the development of national pediatric cancer plans for each country.

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