[...] The Region of the Americas has benefitted from the Pan American Health Organization/World Health Organization (PAHO/WHO) Collaborating Centers (CCs) since 1950 when the first CC was designated at the Johns Hopkins School of Medicine in the United States of America. Since then, the CCs have supported the Organization in several important public health areas, such as nursing, communicable diseases, health promotion, mental health, emergency response, and others. The CCs are comprised of institutions such as universities, hospitals, research institutes, academies or ministries which are designated by the WHO Director-General to undertake activities in alignment with PAHO/WHO objectives and mandates. Given PAHO’s dual role as the WHO Regional Office for the Americas (AMRO) and the Pan American Sanitary Bureau, the WHO CCs located in the Region of the Americas are known as PAHO/WHO CCs. Currently there are over 800 CCs globally across 80 Member States, with currently 174 CCs located in 16 Member States in the Americas, and two CCs located outside the Region [...]