In today's digital age, health data is increasingly coveted, and having legal rules to protect it is not enough to prevent its incorrect, imprudent, or improper use. Breaches of confidentiality, intrusions, and unrestricted access to personal data and sensitive data are a challenge for Latin American and Caribbean countries. This is due to the coexistence of diverse social actors, unspecific regulatory frameworks, data management aimed at reducing IT risks, inequalities in access, and technological-financial gaps, which can be analyzed from a governance perspective. This further demonstrates the region's inability to achieve an equitable distribution of the resources needed to implement policies that guarantee respect for human rights. It is, therefore, imperative to harmonize development objectives with initiatives to protect confidentiality and prevent data leaks, in order to improve the reputation of institutions in terms of credibility and trust, and to enhance the sustainability of systems that focus on people rather than data.