National implementation of HEARTS in Cuba: Management and innovation in a context of limited resources

The HEARTS initiative in the Americas, aimed at reducing cardiovascular mortality through the control of hypertension, required significant contextual adaptation for its successful implementation in Cuba. This article analyzes the organizational strategy and key innovations used to adapt the model to the national context, which enabled the program to expand from a single demonstration site (2016) to 451 primary care centers nationwide (2022).

HEARTS in Guatemala: Implementation experience in addressing cardiorenometabolic risk, 2022–2025

Guatemala faces a growing burden of chronic noncommunicable diseases, with hypertension and type 2 diabetes mellitus being the leading contributors to cardiovascular mortality and progression to chronic kidney disease. In 2022, the Ministry of Public Health and Social Assistance began implementing the Pan American Health Organization/World Health Organization’s HEARTS technical package to strengthen the prevention and clinical management of these conditions in low- and medium-complexity health care facilities.

2025 AHA/ACC blood pressure guideline and HEARTS 2.0: implications for the future evolution of integrated cardiovascular–kidney–metabolic care in the Americas

Hypertension is the leading modifiable risk factor for cardiovascular disease. In 2025, two major evidence-based frameworks evolved in parallel: HEARTS 2.0, an implementation-oriented clinical pathway for integrated cardiovascular–kidney–metabolic (CKM) care through primary health care, and the updated American Heart Association/American College of Cardiology Blood Pressure Guideline, one of the world's leading hypertension guidelines.

HEARTS in the Americas 2026

Cardiovascular diseases continue to be the leading cause of death in the Region of the Americas, accounting for more than 2.2 million deaths annually, and pose a critical challenge to health systems, economic development, and social equity. The absolute number of cases has continued to rise, while the decline in mortality has slowed since the mid-2010s, jeopardizing progress toward the goal of reducing premature mortality from noncommunicable diseases by 30% by 2030.

Latest articles