Clusters of rare disorders and congenital anomalies in South America
Objective
To map geographic clusters of rare disorders and congenital anomalies reported in South America.
Methods
Qualitative systematic review conducted in Medline/PubMed, Lilacs, and Scielo electronic databases to identify studies meeting eligibility criteria. The strategy resulted in 1 672 unique articles, from which 164 were selected for full reading by a pair of reviewers.