The objective of this article is to analyze the contemporary challenges facing digital health, focusing on literacy, media education, and the prevention of disinformation. The study shows that strengthening digital literacy is crucial to empowering health professionals and citizens, enabling them to critically navigate the digital environment and identify reliable information. The results indicate the need for multisectoral collaboration and public policies that prioritize digital inclusion and media education, promoting a safe information environment. It is recommended to implement comprehensive training policies, use advanced technologies to monitor disinformation, and implement specific strategies to reduce inequalities in access to digital technologies. The conclusion is that overcoming these challenges will require continuous efforts between governments, health professionals, educators, and civil society to strengthen public trust and achieve digital resilience.